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There are 8 five-letter words containing D, E, O and U

COUDEcoudé adj. (Of a catheter) Bent at the tip at a 45° angle, like an elbow.
COUDE n. (French) a reflecting telescope in which one or more plane mirrors reflects the light down the polar axis.
DOUCEdouce adj. (Obsolete) Sweet; nice; pleasant.
douce adj. (Dialect) Serious and quiet; steady, not flighty or casual; sober.
DOUCE adj. (French) sweet, pleasant.
DOUSEdouse v. (Transitive, intransitive) To plunge suddenly into water; to duck; to immerse.
douse v. (Intransitive) To fall suddenly into water.
douse v. (Transitive) To put out; to extinguish.
LOUEDLOU v. (Scots) to love, also LOO.
ODEUModeum n. Alternative form of odeon.
ODEUM n. (Latin) a building for the performance of vocal and instrumental music, esp. among the ancient Greeks and Romans, also ODEON.
OUPEDOUP v. to bind with thread, also OOP.
OUTEDouted v. Simple past tense and past participle of out.
OUT v. to reveal.
UREDOuredo n. (Botany, countable) A summer stage in the life history of certain rusts (Uredinales), regarded at one…
uredo n. (Medicine, uncountable) urticaria; nettle-rash.
Uredo prop.n. A taxonomic genus within the order Uredinales.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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