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There are 9 fifteen-letter words containing 2D, M and 2S

CHORDAMESODERMSCHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DEMANDINGNESSESDEMANDINGNESS n. the state of being demanding.
DISACCOMMODATESdisaccommodates v. Third-person singular simple present indicative form of disaccommodate.
DISACCOMMODATE v. to put to inconvenience.
DISCOMMISSIONEDdiscommissioned v. Simple past tense and past participle of discommission.
DISCOMMISSION v. (Milton) to deprive of a commission.
DISCOMMODIOUSLYdiscommodiously adv. In a discommodious manner.
DISCOMMODIOUS adv. inconvenient.
MADDENINGNESSESMADDENINGNESS n. the state of being maddening.
MISGUIDEDNESSESmisguidednesses n. Plural of misguidedness.
MISGUIDEDNESS n. the state of being misguided.
UNDEMANDINGNESSundemandingness n. The quality of being undemanding; lack of difficulty or challenge.
UNDEREMPHASISEDunderemphasised adj. Alternative spelling of underemphasized.
UNDEREMPHASISE v. to emphasise insufficiently, also UNDEREMPHASIZE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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