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There are 12 ten-letter words containing 2D, 2I, P and R

DISPERSOIDdispersoid n. Dispersoids are ultrafine nanometer-scale and numerous finely divided particles of one substance dispersed…
dispersoid n. Colloid.
DISPERSOID n. a substance in a state of dispersion.
DISPIRITEDdispirited v. Simple past tense and past participle of dispirit.
dispirited adj. Without energy, gusto or drive, enervated, without the will to accomplish, disheartened.
DISPIRIT v. to lower in spirits.
DISPRAISEDdispraised v. Simple past tense and past participle of dispraise.
DISPRAISE v. to censure.
DISPRINCEDdisprinced adj. (Nonce word) Made unlike a prince.
DISPRINCED adj. (Tennyson) deprived of the appearance of a prince.
DISPROVIDEdisprovide v. (Obsolete, transitive) Not to provide; to fail to provide.
DISPROVIDE v. (archaic) to fail to provide.
EPIDERMOIDepidermoid adj. Similar to epidermal tissue but not histologically identical, or possibly not so (to the extent known…
epidermoid n. (Pathology) An epidermoid cyst.
EPIDERMOID adj. like epidermis; pertaining to the epidermis.
PERIODIDESperiodides n. Plural of periodide.
PERIODIDE n. an iodid, a salt of hydriodic acid, also PERIODID.
PERIODISEDperiodised v. Simple past tense and past participle of periodise.
PERIODISE v. to divide into periods, also PERIODIZE.
PERIODIZEDperiodized v. Simple past tense and past participle of periodize.
PERIODIZE v. to divide into periods, also PERIODISE.
PREBIDDINGPREBIDDING n. the act of bidding in advance.
PUDDINGIERPUDDINGY adj. like a pudding, soft and stodgy.
PYRALIDIDSPYRALIDID n. a kind of moth, also PYRALID, PYRALIS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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