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There are 18 eight-letter words containing 2D, 2E, I and M

BEDIMMEDbedimmed v. Simple past tense and past participle of bedim.
BEDIM v. to make dim.
DEMISTEDdemisted v. Simple past tense and past participle of demist.
DEMIST v. to clear a windscreen of moisture.
DEMITTEDdemitted v. Simple past tense and past participle of demit.
DEMIT v. to give up an office, resign.
DEPRIMEDdeprimed adj. (Firearms) Pertaining to a cartridge missing is priming/primer.
deprimed v. Past tense of deprime.
DEPRIME v. to remove the primer from eg a shell.
DIADEMEDdiademed v. Simple past tense and past participle of diadem.
diademed adj. Wearing a diadem.
DIADEM v. to adorn with a crown.
EMBODIEDembodied v. Simple past tense and past participle of embody.
EMBODY v. to form into a body, also IMBODY.
IMBEDDEDimbedded v. Simple past tense and past participle of imbed.
IMBED v. to plant firmly, also EMBED.
IMPENDEDimpended v. Simple past tense and past participle of impend.
IMPEND v. to be imminent.
MADEFIEDmadefied v. Simple past tense and past participle of madefy.
MADEFY v. (archaic) to moisten.
MEDIATEDmediated v. Simple past tense and past participle of mediate.
MEDIATE v. to act as an intermediary.
MEDICIDEmedicide n. Medically assisted suicide; suicide accomplished with the assistance of a physician.
MEDICIDE n. a medically assisted suicide.
MILDENEDmildened v. Simple past tense and past participle of milden.
MILDEN v. to make mild, or milder.
MILDEWEDmildewed v. Simple past tense and past participle of mildew.
mildewed adj. Covered with mildew.
MILDEW v. to grow a whitish fungi.
MISDEEDSmisdeeds n. Plural of misdeed.
MISDEED n. an evil act.
MOIDEREDmoidered v. Simple past tense and past participle of moider.
MOIDER v. to confuse, stupefy, also MITHER, MOITHER.
REMEDIEDremedied v. Simple past tense and past participle of remedy.
REMEDY v. to relieve or cure.
REMEIDEDremeided v. Simple past tense and past participle of remeid.
REMEID v. (Scots) to remedy, also REMEAD, REMEDE.
REMINDEDreminded v. Simple past tense and past participle of remind.
REMIND v. to cause to remember.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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