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There are 4 eight-letter words containing D, H, 2I, R and S

DISHERITdisherit v. (Obsolete) To disinherit.
DISHERIT v. (Spenser) to deprive of an inheritance, also DISINHERIT.
HIDROSIShidrosis n. (Physiology, medicine) The formation and excretion of sweat; sweating; perspiration; and (sometimes…
HIDROSIS n. abnormal perspiration.
HIRUDINShirudins n. Plural of hirudin.
HIRUDIN n. a substance present in the salivary glands of leeches, used as an anticoagulant.
RHIZOIDSrhizoids n. Plural of rhizoid.
RHIZOID n. a short hairlike organ in the lower plants, serving as a root.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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