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There are 16 words containing 2D, 2E, M, 2O and S

DECOMPOSED	• decomposed v. Simple past tense and past participle of decompose. • DECOMPOSE v. to fall to pieces.
DISEMBOSOMED	• disembosomed v. Simple past tense and past participle of disembosom. • DISEMBOSOM v. to separate from the bosom, to unburden.
OUTMODEDNESS	• outmodedness n. The condition of being outmoded. • OUTMODEDNESS n. the state of being outmoded.
UNDECOMPOSED	• undecomposed adj. Not decomposed. • UNDECOMPOSED adj. not decomposed.
PSEUDOMONADES	• pseudomonades n. Plural of pseudomonas. • PSEUDOMONAD n. a virgate plant and animal pathogen.
TIMBERDOODLES	• timberdoodles n. Plural of timberdoodle. • TIMBERDOODLE n. the North American woodcock.
CHORDAMESODERM	• chordamesoderm n. (Anatomy) The axial mesoderm, which lies along the central axis under the neural tube and gives rise to the notochord. • CHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DECOMMISSIONED	• decommissioned v. Simple past tense and past participle of decommission. • DECOMMISSION v. to remove (as a ship or nuclear power plant) from service.
DEMYTHOLOGISED	• demythologised v. Simple past tense and past participle of demythologise. • DEMYTHOLOGISE v. to remove mythology from in order to arrive at the basic meaning, also DEMYTHOLOGIZE.
DUODENECTOMIES	• duodenectomies n. Plural of duodenectomy. • DUODENECTOMY n. the surgical removal of the duodenum.
GONADECTOMISED	• gonadectomised v. Simple past tense and past participle of gonadectomise. • GONADECTOMISED adj. having undergone a gonadectomy, removal of the gonads, also GONADECTOMIZED.
OUTMODEDNESSES	• OUTMODEDNESS n. the state of being outmoded.
ADENOIDECTOMIES	• adenoidectomies n. Plural of adenoidectomy. • ADENOIDECTOMY n. the surgical removal of the adenoids, also ADENECTOMY.
CHORDAMESODERMS	• CHORDAMESODERM n. the layer of specialized cells in the middle of a developing embryo which forms the notochord and structures of the central nervous system.
DISCOMBOBERATED	• discomboberated v. Simple past tense and past participle of discomboberate. • DISCOMBOBERATE v. to throw into a state of confusion, also DISCOMBOBULATE.
HOBBLEDEHOYDOMS	• HOBBLEDEHOYDOM n. the state of being a hobbledehoy, an awkward young fellow, also HOBBLEDEHOYHOOD, HOBBLEDEHOYISM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 597 words
Scrabble in French: 28 words
Scrabble in Spanish: 347 words
Scrabble in Italian: 80 words
Scrabble in German: no word
Scrabble in Romanian: 14 words

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