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There are 15 words containing D, R, 2S, 2T and 2U

DISTRUSTFUL	• distrustful adj. (Active sense) Experiencing distrust, showing distrust, wary, sceptical, suspicious, doubtful. • distrustful adj. (Passive sense) Causing or giving rise to distrust. • DISTRUSTFUL adj. having or showing distrust.
SUBSTRUCTED	• substructed v. Simple past tense and past participle of substruct. • SUBSTRUCT v. to build beneath; to lay as a foundation.
SUBSATURATED	• subsaturated adj. Less than fully saturated. • SUBSATURATED adj. incompletely saturated.
UNDERTHRUSTS	• underthrusts v. Third-person singular simple present indicative form of underthrust. • UNDERTHRUST v. to insert (a faulted rock mass) into position under a passive rock mass.
AUTODESTRUCTS	• autodestructs v. Third-person singular simple present indicative form of autodestruct. • AUTODESTRUCT v. to self-destruct.
DISTRUSTFULLY	• distrustfully adv. In a distrustful manner. • DISTRUSTFUL adv. having or showing distrust.
SKUTTERUDITES	• skutterudites n. Plural of skutterudite. • SKUTTERUDITE n. a cubic mineral, cobalt arsenide.
SUPERSTRUCTED	• superstructed v. Simple past tense and past participle of superstruct. • SUPERSTRUCT v. to build on something else as a foundation.
UNDERSTRATUMS	• UNDERSTRATUM n. a stratum under another stratum.
STRUCTURALISED	• structuralised v. Simple past tense and past participle of structuralise. • STRUCTURALISE v. to organize or incorporate into a structure, also STRUCTURALIZE.
SUPERSATURATED	• supersaturated adj. (Chemistry, physics, of a solution) More concentrated than is normally possible. • supersaturated adj. (Physics, of a vapor) Having a vapor pressure higher than is normally possible. • supersaturated v. Simple past tense and past participle of supersaturate.
TRISUBSTITUTED	• trisubstituted adj. (Organic chemistry) substituted with three (identical or different) substituents. • TRISUBSTITUTED adj. having three substituent atoms or groups in the molecule.
DISTRUSTFULNESS	• distrustfulness n. The state or quality of being distrustful or doubtful; distrust; mistrust. • DISTRUSTFUL n. having or showing distrust.
SUPERSTIMULATED	• superstimulated v. Simple past tense and past participle of superstimulate. • SUPERSTIMULATE v. to stimulate beyond a normal level.
ULTRAFASTIDIOUS	• ultrafastidious adj. Extremely fastidious. • ULTRAFASTIDIOUS adj. extremely fastidious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 298 words
Scrabble in French: 53 words
Scrabble in Spanish: 14 words
Scrabble in Italian: 10 words
Scrabble in German: no word
Scrabble in Romanian: 20 words

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