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There are 18 five-letter words containing E, M and 2S

MASESmases v. Third-person singular simple present indicative form of mase.
MASes n. Plural of MAS.
MASE v. to act as a maser, a device used to amplify long-range radar and radio astronomy signals.
MASSEMasse prop.n. A surname from French.
massé n. (Billiards, snooker) A stroke made with the cue held vertically that causes a billiard ball to move in an arc.
MASSE n. (French) a vertical shot in billiards.
MESASmesas n. Plural of mesa.
MESA n. (Spanish) a flat-topped hill with steep sides.
MESESmeses n. Plural of mese.
MESE n. (Greek) in Greek music, the middle string of the lyre; its note.
MESSYmessy adj. (Of a place, situation, person, etc) In a disorderly state; chaotic; disorderly.
messy adj. (Of a person) Prone to causing mess.
messy adj. (Of a situation) Difficult or unpleasant to deal with.
MISESmises n. Plural of mise.
Mises prop.n. Plural of Mis.
MISE n. the issue in a writ of right.
MOSESMoses prop.n. The pharaonic patriarch who led the slaved Hebrews out of Egypt, the brother of Aaron and Miriam described…
Moses prop.n. A male given name from Hebrew.
Moses prop.n. A surname transferred from the given name.
MUSESmuses n. Plural of muse.
muses v. Third-person singular simple present indicative form of muse.
Muses n. Plural of Muse.
MUSSEMUSSE v. to disarrange, to mess, also MUSS.
SAMESsame's cont. (Colloquial) Contraction of same as.
SAME n. the same thing.
SEAMSseams n. Plural of seam.
seams v. Third-person singular simple present indicative form of seam.
SEAM v. to join by sewing together.
SEEMSseems v. Third-person singular simple present indicative form of seem.
SEEM v. to appear to be.
SEISMseism n. A shaking of the Earth’s surface; an earthquake or tremor.
SEISM n. an earthquake.
SEMESsemes n. Plural of seme.
semes v. Third-person singular simple present indicative form of seme.
SEME n. a type of heraldic pattern.
SEMISsemis n. Plural of semi.
semis n. (Historical) A small bronze coin minted during the Roman Republic, valued at half an as.
SEMIS n. (Latin) a coin of ancient Rome.
SMEESsmees n. Plural of smee.
SMEE n. (dialect) a name for various ducks including smew, pochard, also SMEATH.
SMEWSsmews n. Plural of smew.
SMEW n. a bird, the smallest merganser.
STEMSstems n. Plural of stem.
stems v. Third-person singular simple present indicative form of stem.
Stems prop.n. Plural of Stem.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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