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There are 2 five-letter words containing E, N, O, P and R

PREONpreon n. (Physics) A hypothetical point-like particle, supposed to be a subcomponent of quarks and leptons and…
PREON n. a hypothetical particle, a possible constituent of a quark.
PRONEprone adj. Lying face downward.
prone adj. Of the hand, forearm or foot: turned facing away from the body; with the thumb inward or big toe downward.
prone adj. Having a downward inclination or slope.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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