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There are 17 ten-letter words containing E, H, 2M and 2S

CHIMERISMSchimerisms n. Plural of chimerism.
CHIMERISM n. the state of being or creating a genetic chimaera, also CHIMAERISM.
CHUMMINESSchumminess n. The state of being chummy.
CHUMMINESS n. the state of being chummy.
DYSPHEMISMdysphemism n. (Uncountable) The use of a word or phrase carrying negative connotations or imagery (especially one…
dysphemism n. (Countable) A word or phrase that is used to replace another in this way.
DYSPHEMISM n. the substitution of a disagreeable or offensive expression for an agreeable or inoffensive one, e.g. The Holocaust (the dysphemism chosen by Jewish historians to replace the Nazis' ghastly euphemism, The Final Solution).
EMPHYSEMASemphysemas n. Plural of emphysema.
EMPHYSEMA n. a swelling produced by gas or air diffused in the cellular tissue.
EUPHEMISMSeuphemisms n. Plural of euphemism.
EUPHEMISM n. a figure of rhetoric by which an unpleasant or offensive thing is described or referred to by a milder term.
HAMMERLESShammerless adj. Without a hammer.
hammerless adj. Not requiring the use of a hammer.
hammerless adj. (Firearms) Without a visible hammer; said of a gun having a cock or striker concealed from sight, and…
HERMETISMShermetisms n. Plural of hermetism.
HERMETISM n. a system of ideas based on hermetic teachings, also HERMETICISM.
HERMITISMSHERMITISM n. the state of being a hermit.
MECHANISMSmechanisms n. Plural of mechanism.
MECHANISM n. the belief that life is explainable by mechanical forces.
MEPHITISMSmephitisms n. Plural of mephitism.
MEPHITISM n. poisoning by mephitis.
MESOMORPHSmesomorphs n. Plural of mesomorph.
MESOMORPH n. a person of muscular body type.
METHODISMSMethodisms n. Plural of Methodism.
METHODISM n. methodical procedure.
MISHMASHESmishmashes n. Plural of mishmash.
mish-mashes n. Plural of mish-mash.
MISHMASH n. a confused mixture, also MISHMOSH.
MISHMOSHESmishmoshes n. Plural of mishmosh.
MISHMOSH n. a confused mixture, also MISHMASH.
MISMATCHESmismatches n. Plural of mismatch.
mismatches v. Third-person singular simple present indicative form of mismatch.
MISMATCH v. to match badly.
SACHEMDOMSsachemdoms n. Plural of sachemdom.
SACHEMDOM n. the government or jurisdiction of a sachem.
SCHEMATISMschematism n. A schematic representation; a schema.
schematism n. (Astrology) The combination of the heavenly bodies.
SCHEMATISM n. combination of the aspects of heavenly bodies.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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