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There are 17 ten-letter words containing E, M, 2P, S and U

MESOHIPPUSMesohippus prop.n. A taxonomic genus within the family Equidae – an extinct horse of the Early Oligocene.
MESOHIPPUS n. an extinct mammal of the Horse family.
MUDHOPPERSmudhoppers n. Plural of mudhopper.
MUDHOPPER n. a fish of mud flats and mangrove swamps, also MUDSKIPPER.
MUDPUPPIESmudpuppies n. Plural of mudpuppy.
mud␣puppies n. Plural of mud puppy.
MUDPUPPY n. a large salamander, the axolotl.
MUDSKIPPERmudskipper n. Any of various gobies of the subfamily Oxudercinae that are able to survive out of water by breathing…
MUDSKIPPER n. a fish of mud flats and mangrove swamps, also MUDHOPPER.
PAUPERDOMSPAUPERDOM n. the state of being a pauper.
PAUPERISMSpauperisms n. Plural of pauperism.
PAUPERISM n. the state of being a pauper.
PEMPHIGOUSpemphigous adj. Relating to pemphigus.
PEMPHIGOUS adj. relating to pemphigus, a skin disease, characterized by the development of blebs upon different part of the body, also PEMPHIGOID.
POMPELMOUSpompelmous n. (Obsolete) Alternative form of pampelmoes: a pomelo; a grapefruit.
POMPELMOUS n. (Dutch) the shaddock or grapefruit, also PAMPELMOOSE, PAMPELMOUSE, POMELO, POMPELMOOSE, POMPELMOUSE, POMPELO, PUMELO, PUMMELO.
PROMPTURESpromptures n. Plural of prompture.
PROMPTURE n. (Shakespeare) a suggestion.
PROPODEUMSPROPODEUM n. in some Hymenoptera, the first abdominal segment, also PROPODEON.
PUMPHOUSESpumphouses n. Plural of pumphouse.
pump␣houses n. Plural of pump house.
PUMPHOUSE n. a building in which are housed pumps that supply e.g. an irrigation system.
SUPERPIMPSsuperpimps n. Plural of superpimp.
SUPERPIMP n. a pimp controlling other pimps.
SUPPERTIMEsuppertime n. The time when supper takes place.
suppertime n. The time when supper is ready.
supper-time n. Alternative form of suppertime.
SUPPLEMENTsupplement n. Something added, especially to make up for a deficiency.
supplement n. An extension to a document or publication that adds information, corrects errors or brings up to date.
supplement n. An additional section of a newspaper devoted to a specific subject.
SUPPLYMENTsupplyment n. (Obsolete) The act of supplying.
SUPPLYMENT n. (Shakespeare) a supplying or furnishing.
UMPIRESHIPumpireship n. The post or office of umpire.
umpireship n. Arbitration.
UMPIRESHIP n. umpirage; arbitrament.
YUPPIEDOMSYUPPIEDOM n. the state of being a yuppie, also YUPPYDOM.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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