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There are 13 words containing E, L, 2P, S and X

APOPLEXESapoplexes n. Plural of apoplex.
APOPLEX v. to affect with apoplexy.
PERPLEXESperplexes v. Third-person singular simple present indicative form of perplex.
PERPLEX v. to puzzle.
APOPLEXIESapoplexies n. Plural of apoplexy.
APOPLEXY n. a sudden loss of sensation and movement due to a disturbance of blood supply to the brain.
PERPLEXERSperplexers n. Plural of perplexer.
PERPLEXER n. one who perplexes.
SPORTSPLEXsportsplex n. (US) A complex offering sporting facilities.
POMPHOLYXESPOMPHOLYX n. (Greek) a vesicular eruption or eczema chiefly on the palms and soles.
PROPHYLAXESprophylaxes n. Plural of prophylaxis.
PROPHYLAXIS n. preventive treatment against diseases, etc.
UNPERPLEXESunperplexes v. Third-person singular simple present indicative form of unperplex.
UNPERPLEX v. to free from perplexity.
PERPLEXITIESperplexities n. Plural of perplexity.
PERPLEXITY n. the state of being perplexed.
SPORTSPLEXESsportsplexes n. Plural of sportsplex.
PERPLEXEDNESSperplexedness n. The quality of being perplexed; bafflement; confusion.
perplexedness n. (Obsolete) The quality of being intricate, complicated or entangled.
PERPLEXEDNESS n. the state of being perplexed.
PEROXYSULPHURICPEROXYSULPHURIC adj. as in peroxysulphuric acid.
PERPLEXEDNESSESPERPLEXEDNESS n. the state of being perplexed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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