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There are 17 words containing 4E, 2F and R

DEDIFFERENTIATE	• dedifferentiate v. To lose or reverse differentiation. • DEDIFFERENTIATE v. to effect dedifferentiation, a change by which specialized tissue with several cell types reverts to a generalized and simpler form.
DIFFERENTNESSES	• differentnesses n. Plural of differentness. • DIFFERENTNESS n. DIFFERENT, separate, unlike.
EFFERENCE	• efference n. (Uncountable) The state of being efferent. • efference n. (Countable) An efferent process. • EFFERENCE n. the act of conveying outward or away.
EFFERENCES	• efferences n. Plural of efference. • EFFERENCE n. the act of conveying outward or away.
EFFERVESCE	• effervesce v. (Intransitive, of a liquid) To emit small bubbles of dissolved gas; to froth or fizz. • effervesce v. (Intransitive, of a gas) To escape from solution in a liquid in the form of bubbles. • effervesce v. (Intransitive, of a person) To show high spirits.
EFFERVESCED	• effervesced v. Simple past tense and past participle of effervesce. • EFFERVESCE v. to bubble, hiss, and foam as gas escapes.
EFFERVESCENCE	• effervescence n. The escape of gas from solution in a liquid, especially the escape of carbon dioxide from a carbonated drink. • effervescence n. Vivacity. • effervescence n. Foment.
EFFERVESCENCES	• effervescences n. Plural of effervescence. • EFFERVESCENCE n. boiling or bubbling, also EFFERVESCENCY.
EFFERVESCENCIES	• effervescencies n. Plural of effervescency. • EFFERVESCENCY n. boiling or bubbling, also EFFERVESCENCE.
EFFERVESCENCY	• effervescency n. (Archaic) effervescence. • EFFERVESCENCY n. boiling or bubbling, also EFFERVESCENCE.
EFFERVESCENT	• effervescent adj. (Of a liquid) Giving off bubbles; fizzy. • effervescent adj. Vivacious and enthusiastic. • EFFERVESCENT adj. frothing, bubbling.
EFFERVESCENTLY	• effervescently adv. In an effervescent manner. • EFFERVESCENT adv. frothing, bubbling.
EFFERVESCES	• effervesces v. Third-person singular simple present indicative form of effervesce. • EFFERVESCE v. to bubble, hiss, and foam as gas escapes.
EFFERVESCIBLE	• effervescible adj. Capable of effervescing. • EFFERVESCIBLE adj. capable of effervescing.
EFFLORESCENCE	• efflorescence n. (Chemistry) The formation of a powdery surface on crystals, as a hydrate is converted to anhydrous form… • efflorescence n. (Botany) The production of flowers. • efflorescence n. (Construction) An encrustation of soluble salts, commonly white, deposited on the surface of stone…
EFFLORESCENCES	• efflorescences n. Plural of efflorescence. • EFFLORESCENCE n. the act of developing and unfolding as if coming into flower.
SUPEREFFECTIVE	• supereffective adj. Particularly effective. • SUPEREFFECTIVE adj. extremely effective.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 426 words
Scrabble in French: 103 words
Scrabble in Spanish: no word
Scrabble in Italian: 258 words
Scrabble in German: 1 word
Scrabble in Romanian: 8 words

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