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There are 7 words containing 4E, 2P and U

PREPUBESCENCEprepubescence n. The period prior to the onset of puberty; prepuberty.
PREPUBESCENCE n. prepuberty.
PREPUBESCENCESPREPUBESCENCE n. prepuberty.
PSEUDOEPHEDRINEpseudoephedrine n. (Pharmacology) A sympathomimetic alkaloid commonly used as a decongestant; a chemical compound, an isomer…
PSEUDOEPHEDRINE n. a naturally occurring isomer of ephedrine, used in the form of its hydrochloride as a bronchodilator.
PUPPETEEREDpuppeteered v. Simple past tense and past participle of puppeteer.
PUPPETEER v. to operate a puppet.
SUPEREXPENSIVEsuperexpensive adj. Highly expensive.
SUPEREXPENSIVE adj. extremely expensive.
SUPEREXPRESSESsuperexpresses n. Plural of superexpress.
SUPEREXPRESS n. a very fast express.
UNDERPEEPEDunderpeeped v. Simple past tense and past participle of underpeep.
UNDERPEEP v. (Shakespeare) to peep under.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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