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There are 20 words containing 2E, 2F, 2I and O

COEFFICIENTcoefficient adj. Cooperating.
coefficient n. (Mathematics) A constant by which an algebraic term is multiplied.
coefficient n. A number, value, or item that serves as a measure of some property or characteristic.
COEFFICIENTScoefficients n. Plural of coefficient.
coëfficients n. Plural of coëfficient.
COEFFICIENT n. any of the factors of a product considered in relation to a specific factor.
DIFFERENTIATIONdifferentiation n. The act or process of differentiating (generally, without a specialized sense).
differentiation n. (Biology) The process by which the components of multicellular life (Cells, organs, etc.) are produced…
differentiation n. (Biology, evolution) The evolutionary process by which one taxonomic group (Species, genus, variety…
DIFFERENTIATORdifferentiator n. Anything that differentiates, or causes differentiation (in any sense); a distinguishing feature.
DIFFERENTIATOR n. someone who or that which differentiates.
DIFFERENTIATORSdifferentiators n. Plural of differentiator.
DIFFERENTIATOR n. someone who or that which differentiates.
DISAFFECTIONATEdisaffectionate adj. Not disposed to affection; unfriendly.
DISAFFECTIONATE adj. showing disaffection.
EFFICACIOUSNESSefficaciousness n. Quality of being efficacious.
EFFICACIOUS n. having the power to produce a desired effect.
FORESIGNIFIEDforesignified v. Simple past tense and past participle of foresignify.
FORESIGNIFY v. (archaic) to signify in advance.
FORESIGNIFIESforesignifies v. Third-person singular simple present indicative form of foresignify.
FORESIGNIFY v. (archaic) to signify in advance.
INOFFENSIVEinoffensive adj. Not offensive.
inoffensive adj. Harmless.
INOFFENSIVE adj. causing no harm or injury, also UNOFFENSIVE.
INOFFENSIVELYinoffensively adv. In an inoffensive manner.
INOFFENSIVE adv. causing no harm or injury, also UNOFFENSIVE.
INOFFENSIVENESSinoffensiveness n. The state or condition of being inoffensive.
INOFFENSIVE n. causing no harm or injury, also UNOFFENSIVE.
INTEROFFICEinteroffice adj. Taking place between different offices of a single organization or company.
interoffice v. To send something between different offices in an organization.
INTEROFFICE adj. between offices.
INTEROFFICESinteroffices v. Third-person singular simple present indicative form of interoffice.
OFFICIALESEofficialese n. The typical language of officials or official documents; legalistic and pompous language.
OFFICIALESE n. the characteristic language of official statements.
OFFICIALESESofficialeses n. Plural of officialese.
OFFICIALESE n. the characteristic language of official statements.
OFFICIOUSNESSESofficiousnesses n. Plural of officiousness.
OFFICIOUSNESS n. OFFICIOUS, volunteering one's services too eagerly.
REFORTIFIEDrefortified v. Simple past tense and past participle of refortify.
REFORTIFY v. to fortify anew.
REFORTIFIESrefortifies v. Third-person singular simple present indicative form of refortify.
REFORTIFY v. to fortify anew.
SCHIZOAFFECTIVEschizoaffective adj. (Psychiatry) Combining the symptoms of schizophrenia with those of bipolar disorder.
schizoaffective n. A person who has a schizoaffective disorder.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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