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There are 19 words containing E, M, 2P, S and 2U

IMMUNOSUPPRESSimmunosuppress v. (Transitive) To cause immunosuppression in.
IMMUNOSUPPRESS v. to inhibit the body's immune response.
MUDPUPPIESmudpuppies n. Plural of mudpuppy.
mud␣puppies n. Plural of mud puppy.
MUDPUPPY n. a large salamander, the axolotl.
MULTIPURPOSEmultipurpose adj. Designed or intended to fit more than one type of function or application; having multiple uses.
multi-purpose adj. Alternative form of multipurpose.
MULTIPURPOSE adj. having many purposes.
MULTIPURPOSESSorry, definition not available.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PRESUMPTUOUSLYpresumptuously adv. In a presumptuous manner; arrogantly.
PRESUMPTUOUS adv. overstepping due bounds (as of propriety or courtesy).
PSEUDOMORPHOUSpseudomorphous adj. Not having the true form.
PSEUDOMORPHOUS adj. of or like a pseudomorph, also PSEUDOMORPHIC.
PSEUDOPODIUMpseudopodium n. (Cytology) pseudopod.
PSEUDOPODIUM n. a process protruding from the cell of a protozoan, etc., used for movement or feeding.
PUMPHOUSEpumphouse n. A building containing pumping equipment; thus…
pump␣house n. Alternative form of pumphouse.
PUMPHOUSE n. a building in which are housed pumps that supply e.g. an irrigation system.
PUMPHOUSESpumphouses n. Plural of pumphouse.
pump␣houses n. Plural of pump house.
PUMPHOUSE n. a building in which are housed pumps that supply e.g. an irrigation system.
SUPERCOMPUTERsupercomputer n. (Computing) Any computer that has a far greater processing power than others of its generation; typically…
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTINGsupercomputing n. (Computing) The design and use of supercomputers.
SUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
SUPERPHYLUMsuperphylum n. (Taxonomy) A taxonomic category above phylum and below subkingdom.
SUPERPHYLUM n. a taxonomical division above phylum.
SUPERPREMIUMsuperpremium adj. Of greatly superior quality, beyond premium.
superpremium n. A product or brand of greatly superior quality, beyond premium.
SUPERPREMIUM n. a very large premium.
SUPERPREMIUMSsuperpremiums n. Plural of superpremium.
SUPERPREMIUM n. a very large premium.
SUPPEDANEUMsuppedaneum n. A foot-support for a crucified person, projecting from the base of the cross.
suppedaneum n. The platform in front of the altar on which celebrating priest stands.
SUPPEDANEUM n. a support under the foot of a crucified person.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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