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There are 16 words containing 2F, I, M, R and 2S

DISAFFIRMANCESdisaffirmances n. Plural of disaffirmance.
DISAFFIRMANCE n. the act of disaffirming.
DISAFFIRMATIONSdisaffirmations n. Plural of disaffirmation.
DISAFFIRMATION n. the act of disaffirming.
DISAFFIRMSdisaffirms v. Third-person singular simple present indicative form of disaffirm.
DISAFFIRM v. to assert the contrary of; to contradict.
DISAFFORESTMENTdisafforestment n. Disafforestation.
DISAFFORESTMENT n. the act of disafforesting.
DUFFERISMSDUFFERISM n. being a duffer, also DUFFERDOM.
EFFUSIOMETERSeffusiometers n. Plural of effusiometer.
EFFUSIOMETER n. an instrument for comparing the molecular weights of gases.
FORISFAMILIATESforisfamiliates v. Third-person singular simple present indicative form of forisfamiliate.
FORISFAMILIATE v. (Scots) to emancipate from parental authority.
FRAMESHIFTSframeshifts n. Plural of frameshift.
FRAMESHIFT n. a term in genetic manipulation, a type of mutation.
GRIFFINISMSGRIFFINISM n. being like a griffin, in the sense of greenhorn.
INDIFFERENTISMSindifferentisms n. Plural of indifferentism.
INDIFFERENTISM n. the belief that all religions are equally valid.
RUFFIANISMSruffianisms n. Plural of ruffianism.
RUFFIANISM n. being a ruffian.
SHERIFFDOMSsheriffdoms n. Plural of sheriffdom.
SHERIFFDOM n. the office of sheriff.
SUFFRAGETTISMsuffragettism n. The suffragette movement for women’s voting rights.
SUFFRAGETTISM n. belief in the aims of the suffragette.
SUFFRAGETTISMSSUFFRAGETTISM n. belief in the aims of the suffragette.
SUFFRAGISMsuffragism n. (Historical) A political movement in the late 19th century that fought for women’s right to vote in…
SUFFRAGISM n. voting rights.
SUFFRAGISMSSUFFRAGISM n. voting rights.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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