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There are 2 five-letter words containing H, I, O and P

HIPPOhippo n. Clipping of hippopotamus.
HiPPO n. (Business) Initialism of highest-paid person’s opinion.
hippo- pref. Horse.
TOPHItophi n. Plural of tophus.
TOPHUS n. (Latin) a deposit of urates in the tissue around a joint.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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