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There is only one eight-letter word containing H, P, R, U and Z

RHIZOPUSRhizopus prop.n. Zygomycete fungi, the members of which are saprobic and include species which cause rots in fruit and…
RHIZOPUS n. (Greek) any of a genus of mould fungi.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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