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There are 10 eight-letter words containing H, 2I, M, O and S

HOMILIEShomilies n. Plural of homily.
HOMILY n. a sermon.
HOMILISThomilist n. One who prepares homilies; one who preaches to a congregation.
HOMILIST n. one who delivers a sermon.
HOMINIDShominids n. Plural of hominid.
HOMINID n. a manlike creature, also HOMINIAN.
HOMINIEShominies n. Plural of hominy.
HOMINY n. hulled, dry corn.
HOMININShominins n. Plural of hominin.
HOMININ n. any member of the taxonomic tribe Hominini, usually taken to comprise humans and their direct ancestors, but sometimes taken also to include chimpanzees.
HOMINISEHOMINISE v. to alter the environment to conform with evolving man, also HOMINIZE.
ISOCHEIMisocheim n. An isotherm connecting points on a map with equal mean winter temperature.
ISOCHEIM n. a line connecting points of same average winter temperature, also ISOCHEIMENAL, ISOCHIME.
ISOCHIMEISOCHIME n. a line connecting points of same average winter temperature, also ISOCHEIM, ISOCHEIMENAL.
ISTHMOIDisthmoid n. (Graph theory) A set of vertices of a graph after whose deletion the graph is no longer connected.
ISTHMOID adj. pertaining to an isthmus, also ISTHMIC.
PHIMOSISphimosis n. (Medicine) A contraction of the foreskin (either as a stage of development or a pathological condition)…
PHIMOSIS n. (Greek) the abnormal constriction of the opening of the prepuce.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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