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There are 18 words containing I, P, U, Y and Z

EMPYREUMATIZE	• empyreumatize v. (Transitive, obsolete) To burn so as to cause empyreuma in. • EMPYREUMATIZE v. to render empyreumatic, also EMPYREUMATISE.
EMPYREUMATIZED	• empyreumatized v. Simple past tense and past participle of empyreumatize. • EMPYREUMATIZE v. to render empyreumatic, also EMPYREUMATISE.
EMPYREUMATIZES	• empyreumatizes v. Third-person singular simple present indicative form of empyreumatize. • EMPYREUMATIZE v. to render empyreumatic, also EMPYREUMATISE.
EMPYREUMATIZING	• empyreumatizing v. Present participle of empyreumatize. • EMPYREUMATIZE v. to render empyreumatic, also EMPYREUMATISE.
HYPERIMMUNIZE	• hyperimmunize v. (Transitive) To immunize excessively. • HYPERIMMUNIZE v. to induce a high level of immunity or of circulating antibodies in, as by a long course of injections of antigen, also HYPERIMMUNISE.
HYPERIMMUNIZED	• hyperimmunized adj. Excessively immunized, and thus containing a large quantity of (specific) antibodies. • HYPERIMMUNIZE v. to induce a high level of immunity or of circulating antibodies in, as by a long course of injections of antigen, also HYPERIMMUNISE.
HYPERIMMUNIZES	• hyperimmunizes v. Third-person singular simple present indicative form of hyperimmunize. • HYPERIMMUNIZE v. to induce a high level of immunity or of circulating antibodies in, as by a long course of injections of antigen, also HYPERIMMUNISE.
HYPERIMMUNIZING	• hyperimmunizing v. Present participle of hyperimmunize. • HYPERIMMUNIZE v. to induce a high level of immunity or of circulating antibodies in, as by a long course of injections of antigen, also HYPERIMMUNISE.
POLYZOARIUM	• polyzoarium n. (Zoology) A polyzoary. • POLYZOARIUM n. a bryozoan colony or supporting structure.
PUZZLINGLY	• puzzlingly adv. In a puzzling manner. • PUZZLING adv. PUZZLE, to cause uncertainty and indecision in.
SCHIZOPHYCEOUS	• schizophyceous adj. (Zoology) Of or relating to the Schizophyceae, a class of blue-green algae. • SCHIZOPHYCEOUS adj. of or belonging to the Schizophyceae, a group of bluish-green algae.
SULFINPYRAZONE	• sulfinpyrazone n. A uricosuric medication used to treat gout. • SULFINPYRAZONE n. a uricosuric drug used in the long-term treatment of chronic gout.
SULFINPYRAZONES	• sulfinpyrazones n. Plural of sulfinpyrazone. • SULFINPYRAZONE n. a uricosuric drug used in the long-term treatment of chronic gout.
SULPHINPYRAZONE	• sulphinpyrazone n. Alternative form of sulfinpyrazone. • SULPHINPYRAZONE n. a drug used to treat gout.
UNAPPETIZINGLY	• unappetizingly adv. In an unappetizing or unappealing manner. • UNAPPETIZING adv. not appetizing.
UNSYMPATHIZING	• unsympathizing adj. Failing to sympathize; lacking sympathy. • UNSYMPATHIZING adj. not sympathizing, also UNSYMPATHISING.
ZIZYPHUS	• Zizyphus prop.n. Dated form of Ziziphus. • ZIZYPHUS n. (Latin) a shrub or tree of the buckthorn family, aka the jujube tree.
ZIZYPHUSES	• ZIZYPHUS n. (Latin) a shrub or tree of the buckthorn family, aka the jujube tree.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 159 words
Scrabble in French: 21 words
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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