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There are 9 ten-letter words containing 2I, N, P and 2U

CUPIDINOUScupidinous adj. Characterized by or related to cupidity (greed, desire for wealth).
CUPIDINOUS adj. full of desire, amorous.
EPINEURIUMepineurium n. (Anatomy) The connective tissue framework and sheath of a nerve which bind together the nerve bundles…
EPINEURIUM n. the connective tissue framework and sheath of a nerve.
EUPHUISINGeuphuising v. Present participle of euphuise.
EUPHUISE v. to write in an affected literary style, also EUPHUIZE.
EUPHUIZINGeuphuizing v. Present participle of euphuize.
EUPHUIZE v. to write in an affected literary style, also EUPHUISE.
PINGUITUDEpinguitude n. Fatness; obesity; the process of growing fat.
PINGUITUDE n. fatness.
PURLICUINGPURLICUE v. to summarise in conclusion, also PIRLICUE.
SIPUNCULIDsipunculid n. (Zoology) Any member of the clade Sipuncula.
sipunculid n. (Zoology, uncommon) Any member of the family Sipunculidae, the peanut worms.
SIPUNCULID n. a kind of marine worm with a retractile proboscis, also SIPUNCULOID.
UNPURIFIEDunpurified adj. Not purified; impure.
UNPURIFIED adj. not purified.
UPBUILDINGupbuilding v. Present participle of upbuild.
upbuilding n. The process of building something up; gradual development or accumulation.
UPBUILDING n. development; edification.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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