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 There are 4 eight-letter words containing 2I, N, R, 2S and T| INSISTER | • insister n. One who insists. • INSISTER n. one who insists.
 |  | IRONISTS | • ironists n. Plural of ironist. • IRONIST n. one who uses irony.
 |  | SINISTER | • sinister adj. Inauspicious, ominous, unlucky, illegitimate (as in bar sinister). • sinister adj. Evil or seemingly evil; indicating lurking danger or harm.
 • sinister adj. (Archaic) Of the left side.
 |  | SIRTUINS | • sirtuins n. Plural of sirtuin. • SIRTUIN n. any of a group of enzymes which regulate cell metabolism and aging.
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 Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.Definitions are short excerpt from the WikWik.org and 1Word.ws.
 
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