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There are 10 words containing 4I, O, S, U and Z

DISILLUSIONIZE	• disillusionize v. (Transitive) To disillusion, disabuse, free from illusion. • DISILLUSIONIZE v. to free from illusion, also DISILLUSIONISE.
INSOLUBILIZING	• insolubilizing v. Present participle of insolubilize. • INSOLUBILIZE v. to make insoluble, also INSOLUBILISE.
MISUTILIZATION	• misutilization n. Misuse. • MISUTILIZATION n. a wrong utilization, also MISUTILISATION.
BITUMINIZATIONS	• bituminizations n. Plural of bituminization. • BITUMINIZATION n. the act of bituminizing, also BITUMINISATION.
DISILLUSIONIZED	• disillusionized v. Simple past tense and past participle of disillusionize. • DISILLUSIONIZE v. to free from illusion, also DISILLUSIONISE.
DISILLUSIONIZES	• disillusionizes v. Third-person singular simple present indicative form of disillusionize. • DISILLUSIONIZE v. to free from illusion, also DISILLUSIONISE.
ISOIMMUNIZATION	• isoimmunization n. The development of antibodies in response to an isoantigen. • ISOIMMUNIZATION n. the development of antibodies within an individual against antigens from another individual of the same species, also ISOIMMUNISATION.
MISUTILIZATIONS	• misutilizations n. Plural of misutilization. • MISUTILIZATION n. a wrong utilization, also MISUTILISATION.
QUIZZIFICATIONS	• quizzifications n. Plural of quizzification. • QUIZZIFICATION n. quizzing.
SUBCIVILIZATION	• SUBCIVILIZATION n. the state of being subcivilized, also SUBCIVILISATION.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 132 words
Scrabble in French: 11 words
Scrabble in Spanish: 3 words
Scrabble in Italian: 75 words
Scrabble in German: no word
Scrabble in Romanian: 52 words

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