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There are 17 twelve-letter words containing M, R, U and X

AMBIDEXTROUSambidextrous adj. Having equal ability in both hands; in particular, able to write equally well with both hands.
ambidextrous adj. Equally usable by left-handed and right-handed people (as a tool or instrument).
ambidextrous adj. (Archaic) Practising or siding with both parties.
AUXANOMETERSauxanometers n. Plural of auxanometer.
AUXANOMETER n. an instrument for measuring growth of plants.
CIRCUMFLEXEScircumflexes n. Plural of circumflex.
CIRCUMFLEX n. a mark used over a vowel in certain languages or in phonetic keys to indicate quality of pronunciation.
EXTRAMUNDANEextramundane adj. Beyond mundane, beyond ordinary.
extramundane adj. Extraterrestrial; occurring or originating outside of the Earth.
EXTRAMUNDANE adj. beyond the known universe.
EXTRAMURALLYextramurally adv. In an extramural manner.
EXTRAMURAL adv. outside the walls or fortifications; outside, but under the aegis of e.g. a university.
EXTRAMUSICALextramusical adj. Apart from and in addition to music.
EXTRAMUSICAL adj. lying outside the province of music.
HYDROXONIUMShydroxoniums n. Plural of hydroxonium.
HYDROXONIUM n. the obsolete name for the cation H3O+ derived from protonation of water.
INTERMIXTUREintermixture n. A mass formed by mixture; a mass of ingredients mixed.
intermixture n. Admixture; an additional ingredient.
INTERMIXTURE n. a mass formed by mixture.
METROSEXUALSmetrosexuals n. Plural of metrosexual.
METROSEXUAL n. a heterosexual man who spends a lot of time and money on his appearance and likes to shop.
MULTIPLEXERSmultiplexers n. Plural of multiplexer.
MULTIPLEXER n. a device enabling a computer to transmit data to many terminals by switching quickly from one user's data to another, also MULTIPLEXOR.
MULTIPLEXORSmultiplexors n. Plural of multiplexor.
MULTIPLEXOR n. a device enabling a computer to transmit data to many terminals by switching quickly from one user's data to another, also MULTIPLEXER.
PNEUMOTHORAXpneumothorax n. (Medicine) Presence of air inside the pleural cavity, usually caused by injury either to the lung or the chest wall.
PNEUMOTHORAX n. accumulation of air or gas in the pleural cavity.
PORTMANTEAUXportmanteaux n. Plural of portmanteau.
PORTMANTEAU n. (French) a case opening in two parts, used for carrying clothes while traveling, also PORTMANTLE, PORTMANTUA.
SUBMAXILLARYsubmaxillary adj. (Anatomy) Situated under the maxilla, or lower jaw; inframaxillary.
submaxillary adj. (Anatomy) Of or pertaining to the submaxillary gland.
SUBMAXILLARY adj. situated beneath the lower jaw, as in submaxillary gland, a salivary gland discharging beneath tongue.
XERANTHEMUMSxeranthemums n. Plural of xeranthemum.
XERANTHEMUM n. any plant of the Xeranthemum genus of plants of southern Europe, belonging to the thistle family.
XEROMORPHOUSxeromorphous adj. Xeromorphic.
XEROMORPHOUS adj. of parts of a plant, protected against excessive loss of water by thick cuticles, coatings of hairs and similar structural features, also XEROMORPHIC.
XIPHISTERNUMxiphisternum n. (Biology, medicine) Synonym of xiphoid process.
XIPHISTERNUM n. the posterior and smallest of the three divisions of the sternum.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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