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There are 16 eight-letter words containing M, S, T and X

BUXOMESTbuxomest adj. Superlative form of buxom: most buxom.
BUXOM adj. healthily plump.
EXOTISMSexotisms n. Plural of exotism.
EXOTISM n. something exotic.
EXTREMESextremes n. Plural of extreme.
EXTREME n. the highest degree.
MARTEXTSmartexts n. Plural of martext.
MARTEXT n. an ignorant preacher.
MASTIXESMASTIX n. (French) a pale yellow gum resin from certain Mediterranean trees, used for varnish, also MASTIC, MASTICH, MASTICHE.
MATRIXESmatrixes n. Plural of matrix.
MATRIX n. (Latin) the womb; that in which anything is embedded, also MATRICE.
MAXIMISTMAXIMIST n. a habitual maker of maxims.
MEATAXESmeataxes n. Plural of meataxe.
meat␣axes n. Plural of meat axe.
MEATAXE n. a meat cleaver.
MIXTAPESmixtapes n. Plural of mixtape.
mix␣tapes n. Plural of mix tape.
MIXTAPE n. a compilation of songs from various sources.
MIXTIONSmixtions n. Plural of mixtion.
MIXTION n. a mixture of amber mastic and asphaltum.
MIXTURESmixtures n. Plural of mixture.
MIXTURE n. the product of mixing.
TEXTISMStextisms n. Plural of textism.
TEXTISM n. the language, or a particular usage, characteristic of text messages.
TOXEMIAStoxemias n. Plural of toxemia.
TOXEMIA n. blood poisoning due to toxins in blood, also TOXAEMIA.
TRIMIXESTRIMIX n. a mixture of nitrogen, helium and oxygen, used by deep-sea divers.
XANTHAMSXANTHAM n. a gum produced by the culture fermentation of glucose, used as a stabilizer, also XANTHAN.
XANTHISMxanthism n. (Biology, zoology) A yellowish colouring of pigments in hair, skin, feathers, etc.
XANTHISM n. a condition of skin, fur or feathers in which yellow coloration predominates.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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