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There are 3 ten-letter words containing M, N, P, T and Z

NITRAZEPAMnitrazepam n. (Pharmacology) A short-acting hypnotic drug (British trademark Mogadon) of the benzodiazepine group…
NITRAZEPAM n. a hypnotic and tranquillizing drug used for the relief of insomnia.
OPTIMIZINGoptimizing v. Present participle of optimize.
optimizing adj. Carrying out optimization.
OPTIMIZE v. to make as effective as possible, also OPTIMISE.
PUZZLEMENTpuzzlement n. The confusing state of being puzzled; bewilderment.
puzzlement n. A puzzle.
PUZZLEMENT n. the state of being puzzled.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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