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There are 9 ten-letter words containing M, N, P, R and 2U

EPINEURIUMepineurium n. (Anatomy) The connective tissue framework and sheath of a nerve which bind together the nerve bundles…
EPINEURIUM n. the connective tissue framework and sheath of a nerve.
MUMPRENEURmumpreneur n. (Informal) A mother who works as a business entrepreneur in addition to her family commitments.
MUMPRENEUR n. a woman who combines running a business enterprise with looking after her children, also MOMPRENEUR.
PENUMBROUSpenumbrous adj. Partially shaded.
penumbrous adj. Vague; ill-defined; unclear.
PENUMBROUS adj. relating to penumbra, partial shade.
PURDONIUMSpurdoniums n. Plural of purdonium.
PURDONIUM n. a kind of coal-scuttle introduced by a Mr Purdon.
SUPERHUMANsuperhuman adj. Beyond what is possible for a human being.
superhuman n. A human being with remarkable abilities or superpowers.
SUPERHUMAN adj. being above the human.
UNCRUMPLEDuncrumpled v. Simple past tense and past participle of uncrumple.
UNCRUMPLE v. to smooth out, remove the crumpling from.
UNCRUMPLESuncrumples v. Third-person singular simple present indicative form of uncrumple.
UNCRUMPLE v. to smooth out, remove the crumpling from.
UNDERTRUMPundertrump v. (Card games) To play a lower trump card than the previous one in a trick.
UNDERTRUMP v. to play a lower trump on a trick to which a higher trump has already been played.
UNPERFUMEDunperfumed adj. Not perfumed.
UNPERFUMED adj. not perfumed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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