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There are 16 eight-letter words containing M, R, S, 2T and U

MATURESTmaturest adj. Superlative form of mature: most mature.
maturest v. (Archaic) second-person singular simple present form of mature.
MATURE adj. fully developed, also MATURATE.
MISTRUSTmistrust n. Lack of trust or confidence; distrust, untrust.
mistrust v. (Transitive) To have no confidence in (something or someone).
mistrust v. (Transitive) To be wary, suspicious or doubtful of (something or someone).
MISTRUTHmistruth n. Untruth; falsehood.
mistruth n. A statement which, while technically true, is dishonestly misleading. (Can we add an example for this sense?)
MISTRUTH n. a lie.
MISTUTORmistutor v. (Transitive) To tutor badly or amiss.
MISTUTOR v. to instruct badly.
MUTATORSmutators n. Plural of mutator.
MUTATOR n. one that causes a change in form.
OUTSMARToutsmart v. (Transitive) To beat in a competition of wits.
OUTSMART v. to outwit.
SMUTTIERsmuttier adj. Comparative form of smutty: more smutty.
SMUTTY adj. sexually suggestive.
STRATUMSstratums n. Plural of stratum.
STRATUM n. (Latin) a layer of material.
STRIATUMstriatum n. (Anatomy) The caudate nucleus and the lentiform nucleus considered as a single structure.
STRIATUM n. (Latin) part of the forebrain.
STRUMPETstrumpet n. A female prostitute.
strumpet n. A woman who is very sexually active.
strumpet n. A female adulterer.
TANTRUMStantrums n. Plural of tantrum.
TANTRUM n. a fit of rage.
TESTAMURtestamur n. A certificate of successful completion of an examination.
TESTAMUR n. (Latin) a certificate of having passed an examination.
TRITIUMStritiums n. Plural of tritium.
TRITIUM n. an isotope of hydrogen.
TRUMPETStrumpets n. Plural of trumpet.
trumpets n. A plant (Sarracenia flava) with long, hollow leaves.
trumpets v. Third-person singular simple present indicative form of trumpet.
TUTORISMtutorism n. (Archaic) tutorship.
TUTORISM n. the act of tutoring.
YTTRIUMSyttriums n. Plural of yttrium.
YTTRIUM n. (Swedish) a rare earth element.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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