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There are 3 eight-letter words containing 2N, P and X

EXPONENTexponent n. One who expounds, represents or advocates.
exponent n. (Mathematics) The number by which a value (called the base) is said to be raised to a power in exponentiation…
exponent n. (Mathematics, obsolete) The degree to which the root of a radicand is found, for example, the 2 in 2]𝑟=𝑏.
NAPROXENnaproxen n. (Pharmacology) A certain non-steroidal anti-inflammatory drug that inhibits the COX-1 and COX-2 enzymes…
NAPROXEN n. an anti-inflammatory drug.
SIXPENNYsixpenny adj. Worth six pennies.
sixpenny adj. (Dated) Cheap; worthless.
sixpenny n. A publication costing sixpence.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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