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There are 2 eight-letter words containing N, 2O, P and X

OPOPANAXopopanax n. (Obsolete) A gum resin obtained from the root of Opopanax chironium, formerly used in medicine.
opopanax n. A perfume made from the gum resin of various trees.
opopanax n. The popinac or opopanax tree (Acacia farnesiana, syn. Vachellia farnesiana), an acacia of America.
POLYAXONpolyaxon n. (Zoology) In a sponge, a spicule that has more than four centered axes.
POLYAXON n. a nerve cell with multiple branches.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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