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There are 8 words containing N, 2P, 3S and 2U

IMMUNOSUPPRESS	• immunosuppress v. (Transitive) To cause immunosuppression in. • IMMUNOSUPPRESS v. to inhibit the body's immune response.
PERSPICUOUSNESS	• perspicuousness n. The state or characteristic of being perspicuous; perspicuity. • PERSPICUOUSNESS n. the state of being perspicuous.
POPULOUSNESS	• populousness n. The quality of being populous. • POPULOUSNESS n. the state of being populous.
POPULOUSNESSES	• POPULOUSNESS n. the state of being populous.
PURPOSEFULNESS	• purposefulness n. The state of being purposeful. • PURPOSEFUL n. showing purpose.
UNSUPPLENESS	• unsuppleness n. The quality of not being supple. • UNSUPPLENESS n. the state of being unsupple.
UNSUPPLENESSES	• UNSUPPLENESS n. the state of being unsupple.
UNSUPPRESSED	• unsuppressed adj. Not suppressed. • UNSUPPRESSED adj. not suppressed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 99 words
Scrabble in French: 7 words
Scrabble in Spanish: 4 words
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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