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There are 7 twelve-letter words containing O, 2R, U and X

GROUNDPROXESGROUNDPROX n. an altitude warning system in aircraft.
HYDROXYUREAShydroxyureas n. Plural of hydroxyurea.
HYDROXYUREA n. a drug used to treat some forms of leukemia, melanoma, and malignant tumors.
OVEREXPOSUREoverexposure n. Excessive exposure.
overexposure n. Of a famous person, excessive publicity, publication or reporting regarding that person.
overexposure n. (Photography) Exposure of film to light during the development process for a longer time than is required…
PARADOXURINEparadoxurine adj. Of, or pertaining to, the genus Paradoxurus.
PARADOXURINE n. any of a number of palm civet species.
PYRRHULOXIASpyrrhuloxias n. Plural of pyrrhuloxia.
PYRRHULOXIA n. a grey-and-pink crested bunting of Central and SW North America, with a short parrot-like bill.
RETROSEXUALSretrosexuals n. Plural of retrosexual.
RETROSEXUAL n. a man with traditional sexual attitudes.
XEROMORPHOUSxeromorphous adj. Xeromorphic.
XEROMORPHOUS adj. of parts of a plant, protected against excessive loss of water by thick cuticles, coatings of hairs and similar structural features, also XEROMORPHIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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