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There are 9 twelve-letter words containing 2R, 2S, U and Z

DEPRESSURIZEdepressurize v. (Transitive) To reduce the air pressure within a chamber.
depressurize v. (Intransitive) To have the pressure of one’s environmental atmosphere reduced.
DEPRESSURIZE v. to reduce the air pressure in esp. suddenly, also DEPRESSURISE.
MOISTURIZERSmoisturizers n. Plural of moisturizer.
MOISTURIZER n. an agent for moisturising, also MOISTURISER.
PASTEURIZERSpasteurizers n. Plural of pasteurizer.
PASTEURIZER n. an apparatus for pasteurizing, also PASTEURISER.
PRESSURIZERSpressurizers n. Plural of pressurizer.
PRESSURIZER n. an apparatus for pressurizing, also PRESSURISER.
PRESSURIZINGpressurizing v. Present participle of pressurize.
PRESSURIZE v. to place under pressure, also PRESSURISE.
REPRESSURIZErepressurize v. To return to a pressurized state, especially after being depressurized.
REPRESSURIZE v. to pressurize again, also REPRESSURISE.
SCRUTINIZERSscrutinizers n. Plural of scrutinizer.
SCRUTINIZER n. one who scrutinizes, also SCRUTINISER.
SECULARIZERSsecularizers n. Plural of secularizer.
SECULARIZER n. one who secularizes, also SECULARISER.
SUPERBAZAARSsuperbazaars n. Plural of superbazaar.
SUPERBAZAAR n. in India, a large department store or supermarket, esp. one set up as a cooperative store by the government, also SUPERBAZAR.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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