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There are 9 two-letter words containing S

ASas adv. To such an extent or degree; to the same extent or degree.
as adv. Considered to be, in relation to something else; in the relation (specified).
as adv. (Dated) For example; for instance. (Compare such as.)
ESes n. Alternative form of ess (letter ’s’) in compounds such as "es-hook".
es n. (Rare) Alternative form of e’s.
es v. Pronunciation spelling of is.
ISis v. Third-person singular simple present indicative form of be.
is v. (Now colloquial) Used in phrases with existential there when the semantic subject is a third-person plural.
is pron. (Geordie) Alternative spelling of us (“me”).
OSos n. (Anatomy) Synonym of bone.
os n. (Anatomy) An opening or entrance to a passage, particularly one at either end of the cervix, internal…
os n. An osar or esker.
SHsh interj. Alternative spelling of shh.
sh sym. (International standards) ISO 639-1 language code for Serbo-Croatian.
sh sym. Alternative form of sinh (“hyperbolic sine”).
SIsi n. (Music) A syllable used in solfège to represent the seventh note of a major scale.
si sym. (International standards) ISO 639-1 language code for Sinhalese.
Si prop.n. A diminutive of the male given name Simon.
SOso conj. Reduced form of ’so that’, used to express purpose; in order that.
so conj. With the result that; for that reason; therefore.
so conj. Used to connect previous conversation or events to the following question.
STst interj. Expressing a sudden desire for silence.
st n. Abbreviation of street. (Usually as “st.” Also as “st”. Sometimes capitalized.)
st n. Abbreviation of Saint. (Always capitalized.)
USus pron. (Personal) Me and at least one other person; the objective case of we.
us pron. (Commonwealth, colloquial, chiefly with give) Me.
us pron. (Northern England) Our.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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