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There are 7 words containing 2S, U, Y and Z

SCHIZOMYCETOUS	• SCHIZOMYCETOUS adj. of or like a schizomycete, any microscopic organism of the class Schizomycetes, also SCHIZOMYCETIC.
SCHIZOPHYCEOUS	• schizophyceous adj. (Zoology) Of or relating to the Schizophyceae, a class of blue-green algae. • SCHIZOPHYCEOUS adj. of or belonging to the Schizophyceae, a group of bluish-green algae.
SOYUZES	• Soyuzes n. Plural of Soyuz. • SOYUZ n. (Russian) a Soviet manned spacecraft.
SULFINPYRAZONES	• sulfinpyrazones n. Plural of sulfinpyrazone. • SULFINPYRAZONE n. a uricosuric drug used in the long-term treatment of chronic gout.
UNSYSTEMATIZED	• unsystematized adj. Not systematized. • UNSYSTEMATIZED adj. not systematized, also UNSYSTEMATISED.
ZIZYPHUSES	• ZIZYPHUS n. (Latin) a shrub or tree of the buckthorn family, aka the jujube tree.
ZYGOCACTUSES	• ZYGOCACTUS n. a genus of Brazilian cactus, aka the Christmas cactus.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 128 words
Scrabble in French: 60 words
Scrabble in Spanish: 7 words
Scrabble in Italian: no word
Scrabble in German: 1 word
Scrabble in Romanian: no word

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