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There are 3 five-letter words beginning with ASC

ASCONascon n. (Biology) A cavity, in the form of a bag or tube, lined with choanocytes, that forms the structure of sponges.
Ascon prop.n. A surname.
ASCON n. a type of sponge.
ASCOTascot n. Ascot tie.
Ascot prop.n. A town in Sunninghill and Ascot parish, Windsor and Maidenhead borough, Berkshire, England, and the…
ASCOT n. a type of necktie with broad ends.
ASCUSascus n. (Mycology) A sac-shaped cell present in ascomycete fungi; it is a reproductive cell in which meiosis…
ASCUS n. (Greek) an enlarged cell which has formed eight spores.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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