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There are 5 twelve-letter words beginning with GUI

GUILEFULNESS• guilefulness n. The quality of being guileful; cunning or deceit.
• GUILEFULNESS n. the state of being guileful.
GUILLOTINERS• guillotiners n. Plural of guillotiner.
• GUILLOTINER n. one who guillotines.
GUILLOTINING• guillotining n. Gerund of guillotine: an execution by guillotine.
• guillotining v. Present participle of guillotine.
• GUILLOTINE v. to behead with a guillotine.
GUILTINESSES• guiltinesses n. Plural of guiltiness.
• GUILTINESS n. the state of being guilty.
GUITARFISHES• guitarfishes n. Plural of guitarfish.
• GUITARFISH n. a kind of ray, somewhat guitar-like in shape.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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