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There are 10 eight-letter words beginning with HIS

HISSIEST• hissiest adj. Superlative form of hissy: most hissy.
• HISSY adj. temperamental.
HISSINGS• hissings n. Plural of hissing.
• HISSING n. an object of scorn.
HISTAMIN• histamin n. Dated form of histamine.
• HISTAMIN n. a base used in medicine obtained from ergot and present in all the tissues of the body, also HISTAMINE.
HISTIDIN• histidin n. Dated form of histidine.
• HISTIDIN n. an amino acid found in proteins, also HISTIDINE.
HISTIOID• histioid adj. Synonym of histoid.
• HISTIOID adj. resembling the normal tissues; as, histioid tumors, also HISTOID.
HISTOGEN• histogen n. (Biology) Any of the germ layers involved in histogenesis.
• HISTOGEN n. a more or less well-defined region within a plant where tissues undergo differentiation.
HISTONES• histones n. Plural of histone.
• HISTONE n. any of a group of simple proteins present in chromosomes and believed to act as gene inhibitors.
HISTORIC• historic adj. Very important; noteworthy: having importance or significance in history.
• historic adj. Old-fashioned, untouched by modernity.
• historic adj. (Now uncommon) Synonym of historical: of, concerning, or in accordance with recorded history or the…
HISTRION• histrion n. (Obsolete) A stage actor.
• HISTRION n. (archaic) an actor, also HISTRIO.
HISTRIOS• HISTRIO n. (archaic) an actor, also HISTRION.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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