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There are 2 four-letter words beginning with IO

IONSions n. Plural of ion.
Ions prop.n. A surname originating as a patronymic.
Ions prop.n. Plural of Ion.
IOTAiota n. The ninth letter of the Greek alphabet.
iota n. A jot; a very small, insignificant quantity.
IOTA n. (Finance) A bank account that earns interest and pays it to a third party, generally a charity; the…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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