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There are 4 words beginning with ISTHMI

ISTHMI	• isthmi n. Plural of isthmus. • ISTHMUS n. (Latin) a strip of land connecting two larger land masses.
ISTHMIC	• isthmic adj. (Anatomy) Relating to an (anatomical) isthmus. • ISTHMIC adj. pertaining to an isthmus, also ISTHMOID.
ISTHMIAN	• isthmian adj. Of or pertaining to an isthmus, especially to the Isthmus of Corinth, in Greece. • isthmian n. A native or inhabitant of an isthmus. • Isthmian adj. Of or from the Isthmus of Corinth.
ISTHMIANS	• isthmians n. Plural of isthmian. • ISTHMIAN n. a native of an isthmus.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 7 words
Scrabble in French: 2 words
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: 1 word
Scrabble in Romanian: no word

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