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There are 5 four-letter words beginning with LOC

LOCA• loca n. Plural of locum.
• LOCA n. (Nuclear industry) loss-of-coolant accident.
• LOCA n. Initialism of Liquid optically clear adhesive.
LOCH• loch n. (Ireland, Scotland) A lake.
• loch n. (Ireland, Scotland) A bay or arm of the sea.
• loch n. Alternative form of lohoch (“medicine taken by licking”).
LOCI• loci n. Plural of locus.
• LOCI n. an engine used in logging, also LOCIE.
LOCK• lock n. Something used for fastening, which can only be opened with a key or combination.
• lock n. (Computing, by extension) A mutex or other token restricting access to a resource.
• lock n. A segment of a canal or other waterway enclosed by gates, used for raising and lowering boats between levels.
LOCO• loco adv. (Music) A direction in written or printed music to be returning to the proper pitch after having played…
• loco adj. (Colloquial) Crazy.
• loco adj. (Southwestern US) Intoxicated by eating locoweed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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