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There are 9 five-letter words beginning with LOC

LOCAL• local adj. From or in a nearby location.
• local adj. (Computing, of a resource) Connected directly to a particular computer, processor, etc.; able to be accessed offline.
• local adj. (Computing, of a variable or identifier) Having limited scope (either lexical or dynamic); only being…
LOCHE• loche n. Alternative form of loach (“kind of fish”).
• LOCHE n. a fish of the cod family.
LOCHS• lochs n. Plural of loch.
• Lochs prop.n. Plural of Loch.
• LOCH n. (Scots) a lake.
LOCIE• LOCIE n. an engine used in logging, also LOCI.
LOCIS• LOCI n. an engine used in logging, also LOCIE.
LOCKS• locks n. Plural of lock.
• locks n. A head of hair; tresses.
• locks n. (Colloquial) Dreadlocks.
LOCOS• locos n. Plural of loco.
• locos v. Third-person singular simple present indicative form of loco.
• LOCO v. to poison with locoweed.
LOCUM• locum n. (Britain, Australia, informal) Short for locum tenens.
• locum n. (Britain, Australia, informal) A period working as a locum tenens.
• locum n. (Historical) A share in a Genoese trading vessel.
LOCUS• locus n. A place or locality, especially a centre of activity or the scene of a crime.
• locus n. (Mathematics) The set of all points whose coordinates satisfy a given equation or condition.
• locus n. (Genetics) A fixed position on a chromosome that may be occupied by one or more genes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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