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There are 6 five-letter words beginning with LOS

LOSED• losed v. (Obsolete) simple past tense and past participle of lose.
• losed v. (Obsolete) simple past tense and past participle of loose.
• LOSED v. (Spenser) loosed.
LOSEL• losel n. (Archaic) A worthless or despicable person, scoundrel.
• losel adj. Worthless; wasteful.
• LOSEL n. a good for nothing fellow; a vagabond, also LOREL, LORRELL, LOZELL.
LOSEN• LOSEN v. (Spenser) to loosen.
LOSER• loser n. A person who loses; one who fails to win or thrive.
• loser n. Something of poor quality.
• loser n. A person who is frequently unsuccessful in life.
LOSES• loses v. Third-person singular simple present indicative form of lose.
• LOSE v. to misplace or be deprived of.
LOSSY• lossy adj. (Telecommunications) Of a communication channel, subject to loss of signal strength.
• lossy adj. (Power systems) Of an electricity transmission line, subject to various forms of power loss.
• lossy adj. (Computing, of an algorithm for converting or compressing data) Reducing the amount of information in data.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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