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There are 4 six-letter words beginning with LOCU

LOCULE• locule n. (Zoology) A little hollow; a loculus.
• locule n. (Botany) Any of the cells of a compound ovary of a plant.
• LOCULE n. a small, cell-like chamber, also LOCULUS.
LOCULI• loculi n. Plural of loculus.
• LOCULUS n. (Latin) a small, cell-like chamber, also LOCULE.
LOCUMS• locums n. Plural of locum.
• LOCUM n. (Latin) a temporary substitute.
LOCUST• locust n. Any of the grasshoppers, often polyphenic and usually swarming, in the family Acrididae that are very…
• locust n. (Now historical) A fruit or pod of the carob tree.
• locust n. Any of various often leguminous trees and shrubs, especially of the genera Robinia and Gleditsia; the locust tree.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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