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There are 5 six-letter words beginning with MOTI

MOTIER• MOTEY adj. full of motes.
MOTIFS• motifs n. Plural of motif.
• MOTIF n. (French) a distinctive idea, esp. a theme elaborated on in a piece of music, literature, etc.
MOTILE• motile adj. (Biology) In organisms: having the power to move spontaneously.
• motile adj. (Biology) In organs or organelles: capable of producing motion.
• motile adj. (Physiology) In organs: having the power to move their contents, or to change their shape or tension…
MOTION• motion n. (Uncountable) A state of progression from one place to another.
• motion n. (Countable) A change of position with respect to time.
• motion n. (Physics) A change from one place to another.
MOTIVE• motive n. (Obsolete) An idea or communication that makes one want to act, especially from spiritual sources; a divine prompting.
• motive n. An incentive to act in a particular way; a reason or emotion that makes one want to do something; anything…
• motive n. (Obsolete, rare) A limb or other bodily organ that can move.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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