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There are 4 twelve-letter words beginning with MACROC

MACROCEPHALY• macrocephaly n. (Medicine) A condition in which the head is abnormally large.
• macrocephaly n. (Geography) The excessive concentration of population and development in a single centre, to the detriment…
• MACROCEPHALY n. largeness, or abnormal largeness, of the head.
MACROCLIMATE• macroclimate n. The climate of a relatively large geographic area.
• MACROCLIMATE n. large-scale climate.
MACROCYTOSES• macrocytoses n. Plural of macrocytosis.
• MACROCYTOSIS n. the occurrence of macrocytes in the blood.
MACROCYTOSIS• macrocytosis n. The presence of macrocytes in the blood.
• MACROCYTOSIS n. the occurrence of macrocytes in the blood.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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