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There are 4 six-letter words beginning with NIS

NISEIS	• niseis n. Plural of nisei. • NISEI n. (Japanese) a second-generation Japanese immigrant.
NISGUL	• NISGUL n. (dialect) the smallest and weakest in a brood of chickens.
NISHES	• NISH n. (colloquial) nothing.
NISSES	• NISSE n. in Scandinavian folklore, a brownie or goblin, also NIS.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

English Wiktionary: 17 words
Scrabble in French: no word
Scrabble in Spanish: 4 words
Scrabble in Italian: no word
Scrabble in German: 5 words
Scrabble in Romanian: 5 words

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1word.ws to play with words, anagrams, suffixes, prefixes, etc.
Ortograf.ws to look for words.

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