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There are 20 five-letter words beginning with PY

PYATSPYAT n. (Scots) a magpie, also PYET, PIET, PYOT.
PYETSpyets n. Plural of pyet.
PYET n. (Scots) a magpie, also PIET, PYAT, PYOT.
PYGALpygal adj. (Anatomy) Situated in the region of the rump, or posterior end of the backbone; applied especially to…
pygal n. (Anatomy) The posterior median or supracaudal plate of a chelonian carapace.
PYGAL n. the posterior median plate of a chelonian carapace.
PYGMYpygmy n. (Often capitalized) A member of one of various Ancient Equatorial African tribal peoples, notable for…
pygmy n. (Greek mythology) A member of a race of dwarfs.
pygmy n. (Figuratively, derogatory, offensive) Any dwarfish person or thing.
PYINSPYIN n. a protein compound contained in pus.
PYLONpylon n. A gateway to the inner part of an Ancient Egyptian temple.
pylon n. (Electricity) A tower-like structure, usually one of a series, used to support high-voltage electricity cables.
pylon n. (Architecture) A tall steel or concrete tower from which cables are strung.
PYNEDpyned v. Simple past tense and past participle of pyne.
PYNE v. to yearn intensely, also PINE.
PYNESpynes n. Plural of pyne.
Pynes prop.n. Plural of Pyne.
PYNE v. to yearn intensely, also PINE.
PYOIDpyoid adj. (Medicine) Resembling or relating to pus.
PYOID adj. purulent.
PYOTSpyots n. Plural of pyot.
PYOT n. (Scots) a magpie, also PIET, PYAT, PYET.
PYRALpyral adj. Of or pertaining to a pyre.
PYRAL adj. of or pertaining to a pyre.
PYRANpyran n. (Organic chemistry) Any of a class of unsaturated heterocyclic compounds containing a ring of five carbon…
PYRAN n. a type of unsaturated heterocyclic compound.
PYRESpyres n. Plural of pyre.
PYRE n. a pile of combustible material.
PYREXpyrex n. A kind of heat-resistant borosilicate glass, made by mixing a high concentration of boron oxides into…
pyrex n. (By extension) Any borosilicate glass.
pyrex n. (By extension) Any glass capable of withstanding high temperatures, such as tempered glass suitable for cooking.
PYRICPYRIC adj. pertaining to burning.
PYROSpyros n. Plural of pyro.
PYRO n. (short for) pyrogallol, a chemical used in photography.
PYXEDpyxed v. Simple past tense and past participle of pyx.
PYX v. to test newly minted coins.
PYXESpyxes n. Plural of pyx.
PYX v. to test newly minted coins.
PYXIEpyxie n. Archaic form of pixie (“magical creature”).
PYXIE n. a creeping evergreen shrub having small white or pinkish flowers, native to pine barrens of the eastern United States.
PYXISpyxis n. A small box.
pyxis n. (Botany) A capsule in which the lid separates from the top of the fruit to release the seeds; a pyxidium.
pyxis n. A nautical compass.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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