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There are 7 ten-letter words beginning with POLYS

POLYSEMANT	• polysemant n. A word or phrase with more than one meaning. • POLYSEMANT n. a word with many meanings.
POLYSEMIES	• polysemies n. Plural of polysemy. • POLYSEMY n. in linguistics, the state of having more than one meaning.
POLYSEMOUS	• polysemous adj. (Linguistics) Having multiple meanings or interpretations. • POLYSEMOUS adj. having multiple meanings.
POLYSOMICS	• polysomics n. Plural of polysomic. • POLYSOMIC n. a basically diploid chromosome complement, in which some but not all the chromosomes are represented more than twice.
POLYSOMIES	• polysomies n. Plural of polysomy. • POLYSOMY n. a condition in which one or more extra chromosomes are present in the cells of the body.
POLYSTYLAR	• POLYSTYLAR adj. having many columns, also POLYSTYLE.
POLYSTYLES	• polystyles n. Plural of polystyle. • POLYSTYLE n. a building characterized by many columns.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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English Wiktionary: 40 words
Scrabble in French: 2 words
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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